“An Anlytical Study Of Mycobacterial Load In Trunat And Sputum Conversion In Pulmonary Tuberculosis Sputum Smear Positive Patients”

Abstract

Background: Tuberculosis is one of the major health problem worldwide. TB is one of the 10 causes of deaths in India. Accurate diagnosis and treatment plays major role in reduction in mortality and morbidity of tuberculosis. Truenat (Chip based real -time micro -polymerase chain reaction PCR) plays major role in diagnosis of tuberculosis as well as detection of resistance. In this study bacterial load in truenat (PCR) and sputum conversion is analysed .

Materials And Methods: This Analytical  study was conducted at Sri Lalithambigai medical College and Hospital, Adayalampattu, maduravoyal and District TB Centre, Chinna porur ,West Chennai ,Among 318 patients with sputum smear positive, Age group of 18 years and above ,DM, HTN, Smoking, Alcoholic were included in the study.

Result: Most patients were aged between 41-50, Regarding repeat AFB status 13.8% were positive . Bacterial load is highest in age group 51-60, Bacterial load is higher in individual with positive repeat AFB.

Conclusion: Result suggest there is correlation between truenat bacterial load and repeat sputum AFB. Hence monitoring bacterial load in truenat plays vital role in TB  treatment and follow up.